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Full-Spectrum vs. Isolate?

Full-Spectrum vs. Isolate?


The hemp plant is a symphony of over 400 compounds like cannabidiol (CBD), secondary phytocannabinoids like CBG and CBN, as well as terpenoids, terpenes, and flavonoids. A full-spectrum extract derived from industrial hemp means that it contains all phytochemicals naturally occurring in the plant. This means that there is also a negligible THC content—below .3%.  

Terpenes (such as those found in full-spectrum CBD) are volatile molecules responsible for the unique aroma profile of plants, fruits, vegetables, and spices. Aromatherapists have used these terpenes for centuries. Beyond aroma, terpenes bind to different receptors in the body to provide an array of potential health benefits—just like their cannabinoid neighbors. There are over 200 terpenes in full-spectrum hemp.

One of the signature terpenes in cannabis plants is beta-caryophyllene, a gastroprotective compound also found in oregano, black pepper, and leafy greens. That’s why certain cannabis strains are recommended to patients with gastrointestinal issues; these strains also tend to carry a spicy herbal scent.

Flavonoids are known for their antioxidant and anti-inflammatory health benefits. Some flavonoids extracted from the cannabis plant have been tested for pharmacological effects, but scientists are still researching the role flavonoids play in the overall therapeutic effects of cannabis treatment.

Terpenoids are naturally occurring organic chemicals derived from terpenes. Plant terpenoids are used for their aromatic qualities and play a role in traditional herbal remedies.  

From terpenes to phytocannabinoids, all of the compounds found in hemp work synergistically to heighten the positive effects of cannabidiol. 


Cannabidiol can be isolated down to a single molecule. The resulting CBD “isolate” is a white powder, often found in very high (99%+) concentrations. Looking at an ingredients list, isolate-based products will contain “crystalline CBD”.

In CBD isolate, the naturally occurring terpenes and other cannabinoids are removed during processing. This, in turn, means there is no “entourage effect,” which occurs when the vast array of phytocannabinoids found in hemp interact with the human body to produce a stronger effect than any one of those components alone.


At Baseline, we believe that nature knows best and that taking full-spectrum CBD in all its unprocessed glory is the healthiest, most effective way to benefit from everything CBD has to offer. 

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